Gaining Insights into Diabetic Cardiomyopathy from Drosophila
نویسندگان
چکیده
منابع مشابه
Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options.
Diabetic cardiomyopathy is the presence of myocardial dysfunction in the absence of coronary artery disease and hypertension. Hyperglycemia seems to be central to the pathogenesis of diabetic cardiomyopathy and to trigger a series of maladaptive stimuli that result in myocardial fibrosis and collagen deposition. These processes are thought to be responsible for altered myocardial relaxation cha...
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The pathogenesis of diabetic cardiomyopathy (DCM) is partially understood and is likely to be multifactorial, involving metabolic disturbances, hypertension and cardiovascular autonomic neuropathy (CAN). Therefore, an important need remains to further delineate the basic mechanisms of diabetic cardiomyopathy and to apply them to daily clinical practice. We attempt to detail some of these underl...
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ژورنال
عنوان ژورنال: Trends in Endocrinology & Metabolism
سال: 2015
ISSN: 1043-2760
DOI: 10.1016/j.tem.2015.09.009